产品货号：
Z23681
中文名称：
PGRMC1抗体
英文名称：
Anti-PGRMC1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PGRMC1 Antibody |
| 指标别名 | HPR6.6;MPR;PGRMC;PGRMC1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | PGRMC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human PGRMC1 (67-102aa RLKRRDFTPAELRRFDGVQDPRILMAINGKVFDVTK),identical to the related mouse sequence,and different from the related rat sequence by two amino acids. |
| 实际分子量 | 26KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Progesterone receptor membrane component 1 (PGRMC1) is a protein which co-purifies with progesterone binding proteins in the liver and ovary.In humans,the PGRMC1 protein is encoded by the PGRMC1 gene.The Sigma-2 receptor was recently identified as potentially being the same as PGRMC1.The sole biochemical function of PGRMC1 is heme-binding.PGRMC1 shares key structural motifs with cytochrome b5.It binds and activates P450 proteins,which are important in drug,hormone and lipid metabolism.Also,PGRMC1 binds to PAIR-BP1 (plasminogen activator inhibitor RNA-binding protein-1).However,its expression outside of the reproductive tract and in males suggests multiple functions for the protein.These may include binding to Insig (insulin-induced gene),which regulates cholesterol synthesis. |
| Uniprot ID | O00264 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | progesterone receptor membrane component 1 |
| 蛋白名全称 | Membrane-associated progesterone receptor component 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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